Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream Refillable - 21 Peptides, Lightweight Hydration for Firmer, Smoother

Peptide Skinjection Moisture Infusion Cream is a refillable, peptide-rich moisturizer that delivers intense hydration while helping skin appear firmer and smoother without needles.

This lightweight cream from Peter Thomas Roth is formulated to plump and hydrate skin while targeting the visible signs of expression lines, loss of elasticity and uneven texture. Combining 21 amplified peptides and neuropeptides with supportive hydration actives, it aims to restore a bouncy, supple look. The formula also includes gamma proteins and moisturizing agents like squalane, hyaluronic acid, trehalose and cactus flower extract to lock in moisture and improve overall surface radiance.

How does this cream help with fine lines and expression wrinkles?

The moisturizer uses a concentrated peptide complex to help the skin surface look smoother and reduce the appearance of expression lines. Peptides and neuropeptides are supported by proteins that work on texture and tone, producing a visible difference over short-term use.

• Contains 21 amplified peptides and neuropeptides designed to target eleven lines and marionette/pout lines.
• Gamma proteins help improve the appearance of elasticity and skin radiance.
• Consumer perception study showed noticeable improvements in one week for many participants.*

What kind of hydration and texture does the formula deliver?

Despite rich hydration, the cream maintains a lightweight feel that absorbs without heavy residue. It layers well under makeup and other treatments while delivering sustained moisture to leave skin plump and supple.

• Hyaluronic acid attracts and holds moisture for immediate plumping.
• Squalane and trehalose reinforce lipid barrier for long-lasting softness.
• Cactus flower extract provides botanical hydration and a smoother surface feel.

Is the product refillable and how does that affect use?

The Peptide Skinjection Moisture Infusion Cream comes in a refillable format to reduce waste and make replacement simple. Refill design allows you to continue using the same outer jar while swapping in fresh product cartridges as needed.

• Refillable system reduces packaging waste compared with single-use jars.
• Easy-to-change refill cartridges keep the dispenser hygienic.
• Refills keep the formula protected and ready for daily application.

When and how should I include this moisturizer in my routine?

Use it morning and night after cleansing and any lightweight serums to lock in active ingredients and moisture. A small, even layer is enough—gently press it into the face and neck to encourage absorption and support a smooth finish for makeup or daytime SPF.

• Apply after serum and before sunscreen during the day.
• Pair with retinoids or exfoliants at night, allowing time between products if needed.
• Suitable for daily use as part of a multi-step regimen for mature or dehydrated skin.

Who is this for: Peter Thomas Roth Peptide Skinjection Moisture Infusion Cream is intended for anyone noticing loss of firmness, expression lines or persistent dryness who wants a potent, peptide-forward moisturizer without needles. It suits those seeking visible smoothing and plumping with hydrating support, people preferring refillable packaging, and anyone looking to strengthen skin texture and radiance as part of a regular skincare routine.

*Based on a 1-week consumer perception study on 30 women ages 35–65; individual results may vary.

Ingredients

Water/Aqua/Eau, Glycerin, Dimethicone, Olive Oil Decyl Esters, Glycereth-26, Squalane, Butylene Glycol, Behenyl Alcohol, Polysilicone-11, Batyl Alcohol, Cetyl Alcohol, Simmondsia Chinensis (Jojoba) Seed Oil, Hexapeptide-11, Acetyl Hexapeptide-1, Tripeptide-10 Citrulline, Palmitoyl Dipeptide-10, Palmitoyl Hexapeptide-12, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Palmitoyl Tetrapeptide-7, Tripeptide-1, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Cereus Grandiflorus (Cactus) Flower Extract, Squalene, Phytosterols, Trehalose, Silanetriol Trehalose Ether, Biotin, Citric Acid, Lecithin, Sodium Lactate, Hydrogenated Lecithin, Caprylyl Glycol, Sorbic Acid, Mannitol, Amidinobenzyl Benzylsulfonyl D-Seryl Homophenylalaninamide Acetate, Potassium Sorbate, Sodium Benzoate, Glyceryl Stearate, Caprylic/Capric Triglyceride, Leuconostoc/Radish Root Ferment Filtrate, Sodium Hydroxide, Dimethyl Isosorbide, Potassium Hydrolyzed Polygamma-Glutamate, Laureth-12, Laureth-3, Dextran, Tocopherol, Hydroxyethylcellulose, Disodium Phosphate, Sodium Polyglutamate, Ethylhexylglycerin, Sodium Stearoyl Glutamate, Polyglyceryl-10 Myristate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polysorbate 20, Carbomer, Triethanolamine, Sodium Phosphate, Acrylates Copolymer, Mica, Stearyl Alcohol, Phenoxyethanol.