Obagi Medical 360 Retinol 0.5 Cream 1 oz — Entrapped Delivery for Gentle, Gradual Release

Obagi 360 Retinol 0.5 Technology is a 1 oz cream that delivers retinol through an entrapped delivery system to help smooth skin texture and reduce the visible appearance of fine lines with gradual release for minimized irritation.

Formulated for regular at-home use, this cream combines a stabilized retinol with a cream base designed to be tolerated by a wide range of skin types. The entrapped delivery system releases active ingredients over time, aiming to balance effectiveness with gentler skin response. Obagi Medical positions this product as part of a daily skin-renewal routine and as a complement to broader sun protection and moisturization habits.

How does the entrapped retinol delivery system work?

The entrapped delivery system encases retinol molecules so they are released gradually into the skin. This slower release can help reduce the sudden irritation sometimes associated with concentrated retinoids while maintaining activity over several hours.

• Controlled-release retinol for steady exposure
• Designed to lower immediate irritation compared with direct-release retinol
• Cream base supports gentle application and absorption

What visible improvements can I expect and when?

With consistent nightly use, users typically notice smoother skin texture and a reduction in the appearance of fine lines over weeks to months. Results depend on individual skin condition, adherence, and accompanying skincare like sunscreen and moisturizers.

• Smoother texture with ongoing application
• Appearance of fine lines may diminish over time
• Best when combined with daily sun protection

Is this suitable for sensitive or new retinol users?

The cream formulation and gradual-release technology make this product more approachable for sensitive skin or those new to retinol. Start with a lower frequency (every few nights), monitor tolerance, and increase use as skin adjusts.

• Cream base to comfort and hydrate the skin
• Begin every 2–3 nights, then adjust frequency as tolerated
• Pair with moisturizer to reduce dryness or flaking

How should I incorporate Obagi 360 Retinol 0.5 into my routine?

Apply a pea-sized amount to dry skin in the evening, avoiding the eye area and broken skin. Use sunscreen every morning, as retinol can increase sun sensitivity.

• Evening application after cleansing and drying the skin
• Use a small amount and spread evenly across target areas
• Always follow with broad-spectrum SPF during daytime

Who is this for: Obagi 360 Retinol 0.5 Technology is aimed at adults seeking a medically backed retinol option that balances efficacy with tolerability. It suits those who want to address early signs of aging—such as uneven texture and mild lines—while preferring a cream formulation and a controlled-release approach. If you have severely compromised or highly reactive skin, consult a dermatologist before use.

Ingredients

Water (aqua), caprylic/capric triglyceride, glyceryl stearate, cyclopentasiloxane, butylene glycol, stearic acid, butyrospermum parkii (shea) butter, polysorbate 60, stearyl alcohol, glycerin, retinol, polysorbate 20, dimethicone, carthamus tinctorius (safflower) seed oil, calendula officinalis flower extract, camellia oleifera leaf extract, camellia sinensis leaf extract, chamomilla recutita (matricaria) flower-extract, tocopheryl acetate, ascorbic acid, sodium hyaluronate, cyclohexasiloxane, sorbitol, BHT, bisabolol, allyl methacrylates crosspolymer, dimethicone/vinyl dimethicone crosspolymer, dipotassium glycyrrhizate, disodium EDTA, triethanolamine, carbomer, glyceryl acrylate/acrylic acid copolymer, caprylyl glycol, ethylhexylglycerin, hexylene glycol, phenoxyethanol