ma:nyo Bifida Biome Complex Ampoule Serum 50ml — Nighttime barrier repair, 10-type hyaluronic hydration

ma:nyo Bifida Biome Complex Ampoule Serum is a nighttime ampoule that supports skin barrier repair and delivers multi-layer hydration for a refreshed, glowing complexion.

Designed in the Korean skincare tradition, this 50ml ampoule combines a bifida ferment extract with a 7-ferment complex and ten types of hyaluronic acid to target hydration, resilience, and skin texture while you sleep. The lightweight, fast-absorbing formula layers easily under creams or makeup, and the gentle composition suits a wide range of skin types seeking overnight recovery without greasiness.

How does this serum help skin recover overnight?

Applied before bed, the ampoule works with your skin’s natural repair cycle to support barrier recovery and soothe signs of daytime stress like dryness or roughness. The bifida-derived ingredient and ferment blend are selected to help balance the skin microbiome and encourage a smoother surface by morning.

• Bifida ferment extract to support barrier resilience while you sleep
• 7-ferment complex to calm and refresh stressed skin
• Lightweight texture absorbs quickly to aid nighttime routines

What hydration benefits does the 10-type hyaluronic acid deliver?

The formula layers multiple molecular weights of hyaluronic acid to hydrate different skin depths, which helps plump fine lines and reduce surface tightness. This multi-depth hydration creates a fresher look and a softer feel without a heavy residue.

• Short- and long-chain hyaluronic acids for immediate and lasting moisture
• Plumps dehydrated areas to minimize the appearance of fine lines
• Creates a dewy base that improves makeup application and wear

Will this serum work on sensitive or combination skin?

ma:nyo formulated the ampoule to be low-irritation and suitable for dry, oily, and combination types. Its calming ferment blend and non-sticky finish make it a practical nightly step for those seeking barrier care without adding congestion or heaviness.

• Gentle formula tested for everyday use on sensitive skin
• Non-comedogenic texture that layers well for oily or combination skin
• Hydration-focused rather than oil-heavy, for balanced results

How does this ampoule fit into a morning and evening routine?

Use the ampoule at night as the core restorative step, then in the morning it helps maintain moisture and shield skin from daily stressors when paired with sunscreen. The quick-absorbing finish makes it easy to follow with serums, moisturizers, and makeup.

• Night: apply after toner and before cream to support repair while sleeping
• Morning: use a small amount under moisturizer to sustain hydration and create a moisture shield
• Works well layered under sunscreen or lightweight daytime products

Who is this for: This ampoule suits anyone looking to improve skin resilience and surface hydration overnight — ideal for those dealing with environmental stress, seasonal dryness, or texture concerns. It’s aimed at people who want an effective, fast-absorbing ampoule that plays well with both minimal and multi-step skincare routines and is gentle enough for regular use across different skin types.

Ingredients

Water(Aqua), Butylene Glycol, Bifida Ferment Lysate, Glycerin, Niacinamide, 1,2-Hexanediol, Pentylene Glycol, Squalane, Polyglyceryl-10 Laurate, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Carbomer, Hydrogenated Lecithin, Tromethamine, Xanthan Gum, Propanediol, Ethylhexylglycerin, Adenosine, Dextrin, Theobroma Cacao (Cocoa) Seed Extract, Sodium Hyaluronate, Sodium Phytate, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Cutibacterium Granulosum Ferment Extract Filtrate, Caffeine, Leontopodium Alpinum Callus Culture Extract, Physalis Alkekengi Calyx Extract, Hydrolyzed Algin, Aureobasidium Pullulans Ferment, Epigallocatechin Gallate, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Asiaticoside, Asiatic Acid, Madecassic Acid, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Hyaluronic Acid, Copper Tripeptide-1, Hydrolyzed Sodium Hyaluronate, Acetyl Hexapeptide-8, Potassium Hyaluronate