Obagi Medical Obagi360 Retinol 1.0 1 oz — Entrapped High‑Concentration Retinol for Smoother Skin & Reduced Fine Lines

Obagi360 Retinol 1.0 is a high-concentration, entrapped retinol cream formulated to gradually release active retinol for smoother-looking skin and reduced visible fine lines with minimized irritation.

Designed for nightly use as part of an at-home skincare routine, Obagi Medical's Obagi360 Retinol 1.0 pairs a potent retinol level with an encapsulated delivery system that slows release to help skin adapt. The formula targets texture, tone and the look of fine lines while prioritizing tolerability. Clinical data on file at Obagi Cosmeceuticals LLC reports high user satisfaction in short-term use, and the product is part of a dermatologist-tested medical-grade line trusted by skincare professionals.

How does this retinol work without overwhelming sensitive skin?

Rather than delivering all active retinol at once, the product uses an entrapped or encapsulated delivery approach so molecules release gradually into the skin. That measured release helps support efficacy while reducing the intensity of typical retinol-related irritation, allowing many users to build tolerance over time.

• Entrapped delivery system releases retinol slowly for gentler activity
• Nighttime application lowers sun-sensitivity risk compared with daytime use
• Formulation designed to balance potency and tolerability for at-home use

What visible benefits can I expect and how soon?

Users reported perceptible improvements in facial appearance and skin texture within a few weeks when following a consistent regimen. While results vary by individual, the brand’s internal data indicates many see early changes in smoothness and the appearance of lines with continued use.

• High-concentration retinol targets fine lines and texture
• Reported improvement in facial appearance and texture in as little as three weeks (data on file)
• Best results achieved with regular nightly application and sun protection during daytime

How should I introduce Obagi360 Retinol 1.0 into my routine?

Start slowly to allow skin to acclimate: apply a pea-sized amount to clean, dry skin in the evening and increase frequency based on comfort. Always follow with daytime broad-spectrum SPF, because retinol can increase sun sensitivity. If irritation occurs, reduce application frequency or pause until skin normalizes.

• Begin with 1–2 nights per week, then increase as tolerated
• Use a gentle cleanser and avoid layering other strong actives initially
• Daily sunscreen is essential while using retinol products

Is this product safe for different skin types and tones?

Obagi Medical formulates and tests products across diverse skin types and tones, aiming for broad tolerability. While many users with varied skin types can use this product successfully, individual sensitivity differs—patch testing and gradual introduction help identify personal tolerance.

• Part of a dermatologist-tested, physician-endorsed product line
• Designed with controlled-release retinol to improve tolerability across skin types
• Patch test recommended for reactive or highly sensitive skin

Who is this for: Obagi360 Retinol 1.0 is made for adults seeking a potent, doctor-trusted retinol treatment they can use at home to address texture and early signs of aging while limiting irritation. It’s ideal for people comfortable introducing a concentrated retinol gradually into a nighttime routine and who commit to daytime sun protection. Those with severe sensitivity or who are pregnant/nursing should consult a healthcare professional before use.

Ingredients

Water (aqua), caprylic/capric triglyceride, glyceryl stearate, cyclopentasiloxane, butylene glycol, stearic acid, butyrospermum parkii (shea) butter, polysorbate 60, stearyl alcohol, glycerin, allyl methacrylates crosspolymer, retinol, polysorbate 20, dimethicone, simmondsia, chinensis (jojoba) seed oil, chamomilla recutita (matricaria) flower extract, hypericum perforatum flower extract, malva sylvestris (mallow) flower, extract salvia officinalis (sage) leaf extract, sambucus nigra flower extract, cyclohexasiloxane, sorbitol, tocopheryl acetate, ascorbic acid, ubiquinone, sodium hyaluronate, propylene glycol, BHT, bisabolol, dimethicone/vinyl dimethicone crosspolymer, dipotassium glycyrrhizate, disodium EDTA, triethanolamine, carbomer, glyceryl acrylate/acrylic acid copolymer, caprylyl glycol, ethylhexylglycerin, hexylene glycol, phenoxyethanol