Mederma Acne Scar Serum — 1 fl oz Lightweight Triple-Action Formula with Niacinamide & PHA for Smoother, Brighter Skin

Mederma Acne Scar Serum is a concentrated triple-action topical serum formulated with niacinamide, tetrapeptide-30, and polyhydroxy acid to visibly lighten and smooth the appearance of post-acne marks.

This lightweight serum targets the look of discoloration, raised texture, and persistent redness left behind by acne. Clinically shown to produce visible improvement in the appearance of acne scars in as little as four weeks when used consistently, the formula also hydrates the skin and integrates easily into morning and evening routines. From the #1 doctor and pharmacist recommended scar brand in the U.S., the product is designed for regular, topical use and is compatible with most common skincare steps.

How does this serum help reduce visible acne scars?

The serum combines three active approaches: niacinamide for evening skin tone, tetrapeptide-30 to support smoother texture, and a polyhydroxy acid to gently exfoliate and brighten. These ingredients work together to soften the look of raised or discolored marks without heavy occlusion, allowing the surface to appear more uniform over time. Results depend on consistent application and overall skin care habits.

• Niacinamide helps reduce the look of redness and uneven tone.
• Tetrapeptide-30 supports smoother-feeling skin surface.
• Polyhydroxy acid provides gentle exfoliation and hydration.
• Lightweight serum base absorbs quickly under moisturizers and sunscreen.

When should I expect to see improvement, and how should I use it?

In clinical testing, visible improvement in acne scars was reported in about four weeks with regular use; best practice is twice-daily application for up to eight weeks for more noticeable change. Apply a small amount directly to healed acne marks after cleansing and before moisturizer and sunscreen in the morning. Continue nightly as part of your evening routine; avoid applying to open wounds or active acne lesions.

• Apply twice daily (morning and evening) to healed scarred areas.
• Use after cleansing and before moisturizer/sunscreen in AM.
• Do not use on broken or actively inflamed skin.
• Consistency for 4–8 weeks recommended for visible results.

Will this serum work with my current skincare products and sunscreen?

The formulation is designed to layer under common moisturizers and broad-spectrum sunscreens without pilling; it hydrates while delivering active ingredients. Because one component is a mild polyhydroxy acid, pairing with strong exfoliants or retinoids should be done cautiously to minimize irritation. If you use potent active treatments, introduce the serum gradually and monitor how your skin responds.

• Layers well under moisturizer and sunscreen for daytime use.
• Introduce slowly with other exfoliants or retinoids to avoid irritation.
• Suitable for routine double-application (AM/PM) when tolerated.
• HSA/FSA eligible for convenient purchase options.

Who is this for: Mederma Acne Scar Serum is suited for people looking to reduce the visual appearance of healed acne marks—dark spots, uneven tone, and surface texture—without a heavy cream. It’s appropriate for those who want a targeted, dermatologist-recommended scar brand solution that fits easily into existing skincare routines, provided they avoid applying it to open wounds or actively inflamed blemishes. For best outcomes, combine consistent use with sun protection and gentle overall skin care.