Mary&May Spicule Retinol Cream 0.53 oz — Korean micro-spicules retinol booster, pore-refining & soothing

Mary&May Spicule Retinol PDRN Cream is a concentrated Korean night booster that combines marine micro-spicules with slow-release retinol, niacinamide and a soothing PDRN complex to refine pores, improve texture and support sensitive skin.

This lightweight 0.53 oz jar is designed as a targeted, intensive treatment rather than an everyday moisturizer. The formula pairs about 2,000 ppm of marine micro-spicules — tiny, skin-friendly needles that create micro-channels for better ingredient delivery — with 1,000 ppm of encapsulated, slow-release retinol. Supportive actives like niacinamide, ceramide, panthenol and Centella (CICA) help hydrate and calm skin so you can build tolerance to retinol with less visible irritation.

How does the micro-spicule technology help pore appearance?

The marine micro-spicules are extremely small crystals (roughly 80–300 µm) that create very fine channels at the skin surface to improve penetration of active ingredients. They aren’t abrasive when used as directed; instead, they help the slow-release retinol and niacinamide reach more of the surface where pores and texture irregularities occur.

• About 200,000 micro-spicules per jar for targeted delivery
• Spicule size approx. 1/40 the diameter of an average pore
• Results: visibly refined, smoother-looking pores with continued use

Is the retinol suitable for sensitive or retinol-new skin?

This product uses encapsulated (nano-liposome) retinol that releases slowly, intended to reduce peak irritation compared with some standard retinol formulations. Additionally, the formula includes a CICA + PDRN soothing complex plus a Safe 4X Barrier Blend to support the skin while you build tolerance.

• Start 2–3 nights per week and increase gradually
• Formulated fragrance-free and dermatologist-tested
• Includes panthenol, ceramide and hyaluronic acid to help hydration

What results can I expect and how long until I see them?

Users commonly notice a smoother texture and reduced appearance of enlarged pores after several weeks of consistent use, though individual response times vary. The slow-release retinol helps smooth fine lines and refine texture over time while supportive actives reduce the likelihood of excessive flaking.

• Initial subtle smoothing within weeks; more visible refinement over months
• Helps minimize the flaky or dry look often associated with starting retinol
• Best used at night with daytime sunscreen to protect results

How should I incorporate this cream into my routine safely?

Apply a pea-sized amount to clean, dry skin as the final nighttime step, beginning with 2–3 nights weekly and increasing as tolerated. Avoid combining with AHA/BHA or vitamin C on the same nights and always use SPF during the day to reduce sensitivity to sun exposure.

• Night-only treatment; small amount goes a long way
• Do not layer with strong exfoliating acids the same night
• Keep sunscreen in your daytime routine to protect treated skin

Who is this for: Mary&May Spicule Retinol PDRN Cream is aimed at people looking for a potent, targeted retinol booster to refine pores, smooth texture and address early signs of aging while managing sensitivity. It suits those willing to follow a careful build-up schedule and to use this product as an intensive, night-only treatment rather than a daily replacement for a primary moisturizer.

Ingredients

Aqua(Water), Methylpropanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Panthenol, Caprylic/Capric Triglyceride, Polypropylsilsesquioxane, C14-22 Alcohols, Ammonium Acryloyldimethyltaurate/VP Copolymer, Glyceryl Stearate, Cetyl Ethylhexanoate, Vinyl Dimethicone, Macadamia Ternifolia Seed Oil, Brassica Campestris (Rapeseed) Sterols, Polyglyceryl-10 Laurate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C12- 20 Alkyl Glucoside, Arginine, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Cholesterol, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydrolyzed Sponge, Polyisobutene, Gardenia Florida Fruit Extract, Tocopherol, Allantoin, Ethylhexylglycerin, Butyrospermum Parkii (Shea) Butter, Retinol, Xanthan Gum, Hydrogenated Lecithin, Sodium Hyaluronate, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Adenosine, Dextrin, Helianthus Annuus (Sunflower) Seed Oil, Lauryl Glucoside, Polyglutamic Acid, Polyglyceryl-6 Laurate, Disodium EDTA, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Myristyl Glucoside, Stearic Acid, Benzotriazolyl Dodecyl p-Cresol, Glyceryl Acrylate/Acrylic Acid Copolymer, Oleic Acid, PVM/MA Copolymer, Beta-Carotene, Sodium DNA