Dermalogica Phyto Nature E2 Exosome Pre-Serum — 3.4 fl oz Daily Leave-On Enzymatic Exfoliant with Pumpkin & Turmeric Stem Cells

Dermalogica Phyto Nature E2 is a lightweight daily leave-on pre-serum that pairs regenerative exosomes with pumpkin enzymes to resurface skin, smooth texture, and reduce the appearance of fine lines.

Designed as a professional-grade step before serums and moisturizers, this pre-serum uses next-generation exosome technology plus botanical resurfacing enzymes to accelerate surface renewal without gritty particles. The formula aims to brighten skin tone, soften texture, and support visible anti-aging benefits when used morning and night. It is vegan, fragrance-free, and suitable for mature or prematurely aging skin seeking a daily resurfacing boost.

How quickly will I notice smoother skin?

Clinical testing reported visible improvements in fine lines and surface renewal in as soon as two weeks when used twice daily. Individual results vary, but many users experience a more refined texture and improved luminosity within days as dead surface cells are gently cleared.

• Visible reduction in fine lines reported in clinical studies after two weeks
• Daily enzymatic exfoliation promotes quicker surface cell turnover
• Lightweight leave-on formula works under serums and moisturizer

What makes the exosome blend different from typical anti-aging ingredients?

Dermalogica’s next-gen exosome complex is formulated to support regenerative activity across multiple skin layers rather than acting only at the surface. This approach aims to enhance the skin’s natural renewal processes and complement other active treatments in your routine.

• Targets multiple layers of skin for comprehensive support
• Works alongside enzymes to both renew and resurface
• Clinically shown to increase natural regeneration compared with untreated skin

How should I incorporate this into my daily routine?

Apply Phyto Nature E2 to clean, dry skin both morning and night as the first step after cleansing. Allow the pre-serum to absorb fully before layering your regular serums, moisturizers, and sunscreen in the morning.

• Use twice daily for best, consistent results
• Apply before serums to prime skin for better absorption
• Follow with moisturizer and morning SPF to protect renewed skin

Is this suitable for sensitive or reactive skin?

The product is formulated without artificial fragrances and is cruelty-free and vegan, offering a gentler alternative to physical scrubs. Because it uses active enzymes and exosome technology, patch testing is recommended for very reactive skin types and consultation with a professional is advised for compromised skin.

• Fragrance-free and vegan formulation reduces irritation risk
• Enzymatic exfoliation avoids abrasive particles
• Patch test recommended for sensitive or compromised skin

Who is this for: Phyto Nature E2 is intended for people noticing loss of firmness, increased texture, or fine lines who want a daily, non-abrasive resurfacing step. It suits those who prefer a lightweight, leave-on pre-serum that pairs with their existing serums and treatments, especially mature or prematurely aging skin looking for visible renewal without added fragrance.

Ingredients

Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.